Tremblay / Verkhratsky

Microglia

Physiology, Pathophysiology and Therapeutic Potential

Springer

ISBN 978-3-031-55528-2

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320,99 €

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Bibliografische Daten

Fachbuch

Buch. Hardcover

2024

3 s/w-Abbildungen, 72 Farbabbildungen.

In englischer Sprache

Umfang: xiii, 644 S.

Format (B x L): 21 x 27,9 cm

Verlag: Springer

ISBN: 978-3-031-55528-2

Weiterführende bibliografische Daten

Das Werk ist Teil der Reihe: Advances in Neurobiology

auch verfügbar als eBook (PDF) für 320,99 €

Produktbeschreibung

The past decade has witnessed a revolution in our understanding of microglia, especially since their roles in the healthy CNS have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing further insight into their crucial involvement with diseases. Edited by Drs. Marie-Ève Tremblay and Alexei Verkhratsky, Microglia: Physiology, Pathophysiology and Therapeutic Potential shares with the scientific and medical community the latest discoveries in the microglial research field, with a truly comprehensive collection of chapters written by the top specialists across five continents. The book begins by explaining briefly what they are, from both historical and evolutionary points of view, and how they can be studied. The first section explains their physiological roles in the maturation, function, and plasticity of the CNS. The second section focuses on their general involvement in neuropathophysiology, and the third section on their critical implication in specific CNS diseases, including neurotrauma, neuropathic pain, ischemia and stroke, infectious diseases, autoimmune diseases, neurodevelopmental and neuropsychiatric disorders, substance use and addiction, sleep disorders, ageing, and neurodegenerative diseases. The fourth section presents their clinical potential as a targeted therapeutic tool for these CNS diseases.

Autorinnen und Autoren

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Covers the role of microglia in the healthy brain as well as in pathological conditions Presents the first comprehensive coverage of this hot topic Features contributions from the major names in the field across 5 continents

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