Harnessing Nanozymes to Combat Antimicrobial Resistance

This book spotlights the potential of nanozymes in combating antimicrobial resistance (AMR), a growing global health crisis with high mortality and morbidity. Despite progress in understanding AMR, current therapies often fall short. Nanozymes, a novel class of enzyme-mimicking nanomaterials, offer diverse applications to address AMR and related infections. By enhancing targeted drug delivery, nanozyme-based treatments improve efficacy while reducing adverse effects, highlighting their potential to overcome the limitations of existing therapies.

AMR, driven by the overuse and misuse of antibiotics, is an escalating global challenge that results in resistant bacterial strains and significant health burdens. Current treatments lack optimal efficacy, emphasizing the need for innovative approaches. Nanozymes, with their enzyme-like catalytic activities at the nanoscale, present a promising solution to the complexities of AMR and associated infections.

Nanozymes offer a significant advantage in antimicrobial resistance (AMR) management by enhancing the efficacy of treatments. These formulations can navigate biological barriers with precision, improving drug bioavailability and minimizing off-target effects. Additionally, nanozymes facilitate early disease detection through advanced nano-imaging techniques, allowing the identification of infections and resistant bacteria at early stages-crucial for timely interventions. They can also carry anti-inflammatory agents, providing targeted relief and reducing systemic side effects.

In summary, nanozymes are a transformative tool in AMR management, addressing the limitations of current therapies. By improving drug delivery, enabling early detection, and offering precision therapeutics, nanozymes enhance treatment effectiveness while minimizing adverse effects. Their versatility opens avenues for personalized treatment regimens, paving the way for innovative, tailored healthcare solutions that can better meet the challenges of AMR, ultimately improving patient outcomes and public health.

This book targets scientists and researchers in AMR, drug delivery, and nanomaterials, covering AMR fundamentals to advanced nanozyme applications. It offers detailed, up-to-date insights, serving as a vital resource for students, clinicians, academics, and industry professionals across various scientific disciplines.