Synthesis of ginsenoside triterpenoids by engineered Saccharomyces cerevisiae

Ginsenosides are triterpenoids, a class of natural products with many pharmaceutical functions, mainly present in traditional Chinese medicine Panax species (e.g., Panax ginseng, P. notoginseng, and P. quinquifolium). The present study provides a simple strategy to improve the production and export of ginsenosides by engineered yeast, bringing us one step closer to the efficient industrial production of these valuable natural products.