BÜCHER VERSANDKOSTENFREI INNERHALB DEUTSCHLANDS
eBook
Proteinkinase Inhibitors
Springer International Publishing
ISBN 978-3-030-68180-7
Standardpreis
Bibliografische Daten
eBook. PDF
2021
VII, 256 p. 1 illus..
In englischer Sprache
Umfang: 256 S.
Verlag: Springer International Publishing
ISBN: 978-3-030-68180-7
Weiterführende bibliografische Daten
Das Werk ist Teil der Reihe: Topics in Medicinal Chemistry
Produktbeschreibung
This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a comprehensive and authoritative overview of the history and latest developments in the field. Chapters written by experts from industry and academia cover the function, structure and topology of Proteinkinases, molecular modelling, disclose how to achieve high level of selectivity for kinase inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book.
Given its breath, this book will appeal to medicinal chemists, students, researchers and professionals alike.
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