Polymorphism in the Pharmaceutical Industry
Solid Form and Drug Development
Wiley-VCH
ISBN 978-3-527-34040-8
Standardpreis
Bibliografische Daten
Fachbuch
Buch. Hardcover
2019
100 s/w-Abbildungen, 50 Farbabbildungen.
In englischer Sprache
Umfang: XVI, 512 S.
Format (B x L): 17,8 x 25,2 cm
Gewicht: 1111
Verlag: Wiley-VCH
ISBN: 978-3-527-34040-8
Produktbeschreibung
As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided.
Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.
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