RNA Biophysics

This book offers an integrative treatment of RNA biophysics, with thorough and modern coverage of foundational concepts and experimental techniques. It utilizes illustrative case examples in each chapter to elucidate core biophysical principles. The book begins with a broad introduction to the field, followed by chapters devoted to the thermodynamics, structure, and dynamics of RNA. It covers relevant spectroscopic techniques and molecular dynamics simulations, as well as kinetics of tertiary interactions and molecular recognition by RNA using a receptor complex and riboswitches as model systems.