Gadamasetti / Kolodziej

Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry

Using Chemistry and Bioengineering to Improve the Performance of Biologics

Springer

ISBN 978-3-031-62006-5

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Bibliografische Daten

Fachbuch

Buch. Hardcover

2024

24 s/w-Abbildungen, 105 Farbabbildungen, Bibliographien.

In englischer Sprache

Umfang: xxiv, 559 S.

Format (B x L): 15,5 x 23,5 cm

Verlag: Springer

ISBN: 978-3-031-62006-5

Produktbeschreibung

This book outlines how advances in the diverse scientific and engineering disciplines of synthetic biology, DNA synthesis, production of protein therapeutics, and bioinformatics have led to the commercialization of new complex biotherapeutic modalities in modern era, including monoclonal and multi-specific antibodies, antibody drug conjugates (ADC), fusion proteins, CAR-T and CRISPR technologies and applications, mRNA vaccines and more. Enabling operations to bring these life-changing medicines into the hands of the needy patients include regulatory submissions to authorities across the globe, as well as streamlined production across manufacturing networks deemed necessary and are outlined in dedicated chapters. Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance of Biologics captures the state of the art for many of these new modalities, offering innovative approaches to treat, prevent, and in some providential cases, cure the disease. This book will be of significant interest for many disciplines engaged jointly as teams convergently in delivering these medicines: bioprocess engineers, biologists, chemists, bioengineers, genetic engineers, healthcare professionals, regulatory bodies, among pharmaceutical industry professionals as well as in academic circles.

Autorinnen und Autoren

Kundeninformationen

Provides a comprehensive overview of the state of the art, fundamental principles, and challenges inherent in developing biologic drug therapy Explores how process chemistry in biologics and bioengineering can lead to applied functional outcomes in genetic engineering and gene therapy Edited by world-renown experts, with chapters written by the global subject matter experts in their respective fields

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