Erschienen: 27.10.2015 Abbildung von Zegzouti / Goueli | Kinase Screening and Profiling | 1st ed. 2016 | 2015 | Methods and Protocols | 1360

Zegzouti / Goueli

Kinase Screening and Profiling

Methods and Protocols

lieferbar (3-5 Tage)

ca. 149,79 €

inkl. Mwst.

1st ed. 2016 2015. Buch. x, 223 S. 19 s/w-Abbildungen, 26 Farbabbildungen, 13 s/w-Tabelle, Bibliographien. Hardcover

Humana. ISBN 978-1-4939-3072-2

Format (B x L): 17,8 x 25,4 cm

Gewicht: 6459 g

In englischer Sprache

Das Werk ist Teil der Reihe: Methods in Molecular Biology; 1360

Produktbeschreibung

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.

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