Erschienen: 29.10.2016 Abbildung von Yokomori / Shirahige | Cohesin and Condensin | 1st ed. 2017 | 2016 | Methods and Protocols | 1515

Yokomori / Shirahige

Cohesin and Condensin

Methods and Protocols

lieferbar (3-5 Tage)

ca. 139,09 €

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1st ed. 2017 2016. Buch. xii, 276 S. 8 s/w-Abbildungen, 33 Farbabbildungen, Bibliographien. Hardcover

Humana. ISBN 978-1-4939-6543-4

Format (B x L): 17,8 x 25,4 cm

Gewicht: 6879 g

In englischer Sprache

Das Werk ist Teil der Reihe: Methods in Molecular Biology; 1515

Produktbeschreibung

The volume provides comprehensive, state-of-the-art experimental techniques that are now available to dissect the molecular mechanisms of regulation and function of cohesin and the related factor condensin in vitro and in vivo across different model organisms, as well as in human cells. Cohesin and Condensin: Methods and Protocols is divided into three parts: Part I explores various in vitro and in vivo systems used to study the fundamental mechanism of cohesin regulation in mitosis and meiosis; Part II summarizes experimental systems in a variety of organisms that are used to address interphase functions of cohesin and Nipbl in gene regulation and chromatin interaction, ribosome biogenesis and DNA repair, which contribute significantly to cohesion-associated disorders; Part III covers related condensin complex and describes techniques to study its role in mitosis and interphase. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Cohesin and Condensin: Methods and Protocols is a valuable resource for diverse audiences with interests in the relationship between chromatin organization and genomic functions.

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