Erschienen: 28.12.2016 Abbildung von Williams III / Watts / Miller | Formulating Poorly Water Soluble Drugs | 2nd ed. 2016 | 2016 | 22

Williams III / Watts / Miller

Formulating Poorly Water Soluble Drugs

Buch. Hardcover

2nd ed. 2016. 2016

xiv, 779 S.

Springer. ISBN 978-3-319-42607-5

Format (B x L): 15,5 x 23,5 cm

Gewicht: 1352 g


The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop


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