Erschienen: 17.11.2016 Abbildung von Williams / Daviter | Protein-Ligand Interactions | Softcover reprint of the original 2nd ed. 2013 | 2016

Williams / Daviter

Protein-Ligand Interactions

Methods and Applications

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ca. 176,54 €

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Softcover reprint of the original 2nd ed. 2013 2016. Buch. x, 530 S. 101 s/w-Abbildungen, 45 Farbabbildungen, 16 s/w-Tabelle, Bibliographien. Softcover

Humana Press. ISBN 978-1-4939-5873-3

Format (B x L): 17,8 x 25,4 cm

Gewicht: 1016 g

In englischer Sprache

Das Werk ist Teil der Reihe: Methods in Molecular Biology; 1008

Produktbeschreibung

Proteins are the cell’s workers, their messengers and overseers. In these roles, proteins specifically bind small molecules, nucleic acid and other protein partners. Cellular systems are closely regulated and biologically significant changes in populations of particular protein complexes correspond to very small variations of their thermodynamics or kinetics of reaction. Interfering with the interactions of proteins is the dominant strategy in the development of new pharmaceuticals. Protein Ligand Interactions: Methods and Applications, Second Edition provides a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins. From the initial discovery of natural substrates or potential drug leads, to the detailed quantitative understanding of the mechanism of interaction, all stages of the research process are covered with a focus on those techniques that are, or are anticipated to become, widely accessible and performable with mainstream commercial instrumentation. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and accessible, Protein Ligand Interactions: Methods and Applications, Second Edition serves as an ideal guide for researchers new to the field of biophysical characterization of protein interactions – whether they are beginning graduate students or experts in allied areas of molecular cell biology, microbiology, pharmacology, medicinal chemistry or structural biology.

Gesamtwerk

Die 8. Auflage ist wieder auf sechs Bände angelegt. Darin finden sich übersichtlich und in systematischer Gliederung Vertragsmuster aus der Feder erfahrener Experten. Jedem dieser Muster folgen Anmerkungen, mit denen der dem Vertragsentwurf zu Grunde liegende Sachverhalt und die Gründe für die Wahl des spezifischen Formulars erläutert werden.

Autoren

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