Erschienen: 30.08.2016 Abbildung von Weiner / Kelley | Translating Molecular Biomarkers into Clinical Assays | 1st ed. 2016 | 2016 | Techniques and Applications | 21

Weiner / Kelley

Translating Molecular Biomarkers into Clinical Assays

Techniques and Applications

Buch. Hardcover

1st ed. 2016. 2016

xiii, 212 S. 8 s/w-Abbildungen, 16 Farbabbildungen, 20 Farbtabellen, Bibliographien

In englischer Sprache

Springer. ISBN 978-3-319-40792-0

Format (B x L): 15,5 x 23,5 cm

Gewicht: 508 g

Produktbeschreibung

This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.

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