Erschienen: 14.05.2010 Abbildung von Uversky / Longhi | Assessing Structures and Conformations of Intrinsically Disordered Proteins | 2010

Uversky / Longhi

Assessing Structures and Conformations of Intrinsically Disordered Proteins

2010. Buch. 744 S. Hardcover

Wiley. ISBN 978-0-470-34341-8

Format (B x L): 16,4 x 23,8 cm

Gewicht: 1211 g

In englischer Sprache

Produktbeschreibung

Instrumental techniques for analyzing intrinsically disordered proteins

The recently recognized phenomenon of protein intrinsic disorder is gaining significant interest among researchers, especially as the number of proteins and protein domains that have been shown to be intrinsically disordered rapidly grows. The first reference to tackle this little-documented area, Instrumental Analysis of Intrinsically Disordered Proteins: Assessing Structure and Conformation provides researchers with a much-needed, comprehensive summary of recent achievements in the methods for structural characterization of intrinsically disordered proteins (IDPs).?

Chapters discuss:
* Assessment of IDPs in the living cell
* Spectroscopic techniques for the analysis of IDPs, including NMR and?EPR spectroscopies, FTIR, circular dichroism, fluorescence spectroscopy, vibrational methods, and single-molecule analysis
* Single-molecule techniques applied to the study of IDPs
* Assessment of IDP size and shape
* Tools for the analysis of IDP conformational stability
* Mass spectrometry
* Approaches for expression and purification of IDPs

With contributions from an international selection of leading researchers, Instrumental Analysis of Intrinsically Disordered Proteins: Assessing Structure and Conformation fills an important need in a rapidly growing field. It is required reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, physiologists, and specialists in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.

Gesamtwerk

Die 8. Auflage ist wieder auf sechs Bände angelegt. Darin finden sich übersichtlich und in systematischer Gliederung Vertragsmuster aus der Feder erfahrener Experten. Jedem dieser Muster folgen Anmerkungen, mit denen der dem Vertragsentwurf zu Grunde liegende Sachverhalt und die Gründe für die Wahl des spezifischen Formulars erläutert werden.

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