Erschienen: 08.11.2019 Abbildung von Silvestri / Lichterfeld | HIV-1 Latency | Softcover reprint of the original 1st ed. 2018 | 2019 | 417

Silvestri / Lichterfeld

HIV-1 Latency

lieferbar, ca. 10 Tage

139,09 €

inkl. Mwst.

Softcover reprint of the original 1st ed. 2018 2019. Buch. vii, 248 S. Bibliographien. Softcover

Springer. ISBN 978-3-030-13214-9

Format (B x L): 15,5 x 23,5 cm

In englischer Sprache

Produktbeschreibung

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.

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