Dynamic Stereochemistry

The present book describes the applications of the principles of stereochemistry in organic reactions (called dynamic stereochemistry). The stereochemical aspects of substitution, addition, elimination (including fragmentations) reactions and rearrangements are discussed in a most systematic way. The application of the allylic strains, I-strain, alkyl ketone effects, anomeric effect, etc., are illustrated with numerous examples. An introduction to different approaches to the stereoselective reactions are given. Double stereodifferentiation – matched and mismatched pair of reactants – is also discussed at an elementary level. Intramolecular reactions including those involving the application of tethers, and transannular reactions are discussed. Different stereoselective synthetic methods for the olefins are discussed and summarised. A separate chapter on pericyclic reactions that are highly stereospecific in nature is presented. Problems (including multiple choice questions as well) are given in the exercises of each chapter and their solution is given at the end. Appendix II is totally devoted to MCQ. The teaching and learning of this subject are the main purpose of the book.