Erschienen: 31.10.2002 Abbildung von Naoi / Maruyama / Collins / Youdim / Parvez | Milestones in Neurotoxicity and Neuroprotection: A Tribute to Professor Toshiharu Nagatsu | 2002

Naoi / Maruyama / Collins / Youdim / Parvez

Milestones in Neurotoxicity and Neuroprotection: A Tribute to Professor Toshiharu Nagatsu

lieferbar, ca. 4 Wochen

ca. 97,31 €

inkl. Mwst.

2002. Buch. 154 S. Hardcover

ELSEVIER SCIENCE & TECHNOLOGY. ISBN 978-0-444-51036-5

Format (B x L): 28 x 21,6 cm

In englischer Sprache

Produktbeschreibung

This book summarizes recent advances in understanding the mechanism underlying the selective cell death of dopamine neurons in Parkinson's disease. MPTP, endogenous neurotoxins, L-DOPA, and metal were proved to induce apoptosis and necrosis in neurons. The relationship of these causal factors to the pathogenesis of Parkinson's disease was discussed to give us overviews on the role of neurotoxins in this degenerative disorder. This title further presents the intracellular signal transduction, and the related enzymes and other factors involved in dopaminergic neuronal death. Recent results on intracellular mechanism of neuroprotection are presented, suggesting that neuroprotection as a causal therapy of neurodegenerative disorders may become practical in near future. This book shows new neuroprotective agents, such as propargylamine derivatives and neurotrophins, and the intracellular mechanism to prevent the activation of apoptotic cascade in neurons. The authors of this book are active researchers participating in these subjects and the readers will find the knowledge and techniques for the study on neurotoxicity and neuroprotection, and the strategy for future research on these important subjects in clinical and basic neurology and neurosciences.

The book is dedicated to Professor Toshiharu Nagatsu, a pioneer in the search for pathogenic factors in Parkinson's disease. The book is reprinted from the journal 'Neurotoxicology and Teratology', Volume 24/5.

Gesamtwerk

Die 8. Auflage ist wieder auf sechs Bände angelegt. Darin finden sich übersichtlich und in systematischer Gliederung Vertragsmuster aus der Feder erfahrener Experten. Jedem dieser Muster folgen Anmerkungen, mit denen der dem Vertragsentwurf zu Grunde liegende Sachverhalt und die Gründe für die Wahl des spezifischen Formulars erläutert werden.

Autoren

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