Erschienen: 06.08.2003 Abbildung von Nag | Blood'Brain Barrier | 2003 | Biology and Research Protocols | 89

Nag

Blood'Brain Barrier

Biology and Research Protocols

lieferbar ca. 10 Tage als Sonderdruck ohne Rückgaberecht

ca. 213,99 €

inkl. Mwst.

2003. Buch. xiv, 550 S. Bibliographien. Hardcover

Humana. ISBN 978-1-58829-073-1

Format (B x L): 17,8 x 25,4 cm

Gewicht: 1373 g

In englischer Sprache

Das Werk ist Teil der Reihe: Methods in Molecular Medicine; 89

Produktbeschreibung

Blood–brain barrier (BBB) breakdown leading to cerebral edema occurs in many brain diseases—such as trauma, stroke, inflammation, infection, and tumors—and is an important factor in the mortality arising from these con- tions. Despite the importance of the BBB in the pathogenesis of these diseases, the molecular mechanisms occurring at the BBB are not completely und- stood. In the last decade a number of molecules have been identified not only in endothelial cells, but also in astrocytes, pericytes, and the perivascular cells that interact with endothelium to maintain cerebral homeostasis. However, the precise cellular interactions at a molecular level in steady states and d- eases have still to be determined. The introduction of new research techniques during the last decade or so provide an opportunity to study the molecular mec- nisms occurring at the BBB in diseases. The Blood–Brain Barrier: Biology and Research Protocols provides the reader with details of selected morphologic, permeability, transport, in vitro, and molecular techniques for BBB studies, all written by experts in the field. Each part is preceded by a review that emphasizes the advantages and pitfalls of particular techniques, as well as offering much relevant current information. The techniques provided will be helpful to both beginners in BBB research and those more experienced investigators who wish to add a specific technique to those already available in their laboratories.

Gesamtwerk

Die 8. Auflage ist wieder auf sechs Bände angelegt. Darin finden sich übersichtlich und in systematischer Gliederung Vertragsmuster aus der Feder erfahrener Experten. Jedem dieser Muster folgen Anmerkungen, mit denen der dem Vertragsentwurf zu Grunde liegende Sachverhalt und die Gründe für die Wahl des spezifischen Formulars erläutert werden.

Autoren

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