Erschienen: 30.09.2016 Abbildung von Müller / Cerdan | Comprehensive Analysis of Parasite Biology | 1. Auflage | 2016 | beck-shop.de

Müller / Cerdan / Radulescu

Comprehensive Analysis of Parasite Biology

From Metabolism to Drug Discovery

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185,00 €

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Buch. Hardcover

2016

XXIV, 548 S.

In englischer Sprache

Wiley-VCH. ISBN 978-3-527-33904-4

Format (B x L): 17 x 24,4 cm

Gewicht: 1352 g

Das Werk ist Teil der Reihe: Drug Discovery in Infectious Diseases

Produktbeschreibung

Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

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