Erschienen: 12.12.2012 Abbildung von Morimoto / Christen | Protein Quality Control in Neurodegenerative Diseases | 2012

Morimoto / Christen

Protein Quality Control in Neurodegenerative Diseases

2012. Buch. xii, 136 S. 10 s/w-Tabelle, Bibliographien. Hardcover

Springer. ISBN 978-3-642-27927-0

Format (B x L): 15,5 x 23,5 cm

Gewicht: 391 g

In englischer Sprache

Produktbeschreibung

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

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