Erschienen: 16.12.2014 Abbildung von Maxwell / Roskelley | Genomic Instability and Cancer Metastasis | 2014 | Mechanisms, Emerging Themes, a... | 20

Maxwell / Roskelley

Genomic Instability and Cancer Metastasis

Mechanisms, Emerging Themes, and Novel Therapeutic Strategies

2014. Buch. x, 247 S. 1 s/w-Abbildung, 18 Farbabbildungen, 5 s/w-Tabelle, Bibliographien. Hardcover

Springer. ISBN 978-3-319-12135-2

Format (B x L): 15,5 x 23,5 cm

Gewicht: 555 g

In englischer Sprache

Produktbeschreibung

Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1  outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas.

Autoren

  • Dieses Set enthält folgende Produkte:
      Auch in folgendem Set erhältlich:
      • nach oben

        Ihre Daten werden geladen ...