Erschienen: 28.03.2008 Abbildung von Mandoiu / Zelikovsky | Bioinformatics Algorithms | 2008

Mandoiu / Zelikovsky

Bioinformatics Algorithms

Techniques and Applications

lieferbar, ca. 4 Wochen

ca. 162,00 €

inkl. Mwst.

2008. Buch. 520 S. Hardcover

WILEY. ISBN 978-0-470-09773-1

Format (B x L): 16,4 x 23,7 cm

Gewicht: 861 g

In englischer Sprache

Das Werk ist Teil der Reihe: Wiley Series in Bioinformatics


Presents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology

This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers:

General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seeding, and approximation algorithms

Algorithms and tools for genome and sequence analysis, including formal and approximate models for gene clusters, advanced algorithms for non-overlapping local alignments and genome tilings, multiplex PCR primer set selection, and sequence/network motif finding

Microarray design and analysis, including algorithms for microarray physical design, missing value imputation, and meta-analysis of gene expression data

Algorithmic issues arising in the analysis of genetic variation across human population, including computational inference of haplotypes from genotype data and disease association search in case/control epidemiologic studies

Algorithmic approaches in structural and systems biology, including topological and structural classification in biochemistry, and prediction of protein-protein and domain-domain interactions

Each chapter begins with a self-contained introduction to a computational problem; continues with a brief review of the existing literature on the subject and an in-depth description of recent algorithmic and methodological developments; and concludes with a brief experimental study and a discussion of open research challenges. This clear and approachable presentation makes the book appropriate for researchers, practitioners, and graduate students alike.

Ion I. M?Andoiu, PhD, is Assistant Professor in the Computer Science and Engineering Department at the University of Connecticut. His research focuses on the design and analysis of exact and approximation algorithms for NP-hard optimization problems, particularly in the areas of bioinfor-matics and computational molecular biology, VLSI computer-aided design and manufacturing, and ad-hoc wireless networks.


Die 8. Auflage ist wieder auf sechs Bände angelegt. Darin finden sich übersichtlich und in systematischer Gliederung Vertragsmuster aus der Feder erfahrener Experten. Jedem dieser Muster folgen Anmerkungen, mit denen der dem Vertragsentwurf zu Grunde liegende Sachverhalt und die Gründe für die Wahl des spezifischen Formulars erläutert werden.


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