Ankündigung Erscheint vsl. Januar 2021 Abbildung von Lü / Wang | Modeling and Analysis of Bio-molecular Networks | 1. Auflage | 2021 |

Lü / Wang

Modeling and Analysis of Bio-molecular Networks

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Buch. Hardcover

1st ed. 2020. 2021

xxi, 464 S. 21 s/w-Abbildungen, 123 Farbabbildungen, 124 Farbtabellen, Bibliographien.

In englischer Sprache

Springer. ISBN 9789811591433

Format (B x L): 15,5 x 23,5 cm


This book addresses a number of questions from the perspective of complex systems: How can we quantitatively understand the life phenomena? How can we model life systems as complex bio-molecular networks? Are there any methods to clarify the relationships among the structures, dynamics and functions of bio-molecular networks? How can we statistically analyse large-scale bio-molecular networks?

Focusing on the modeling and analysis of bio-molecular networks, the book presents various sophisticated mathematical and statistical approaches. The life system can be described using various levels of bio-molecular networks, including gene regulatory networks, and protein-protein interaction networks. It first provides an overview of approaches to reconstruct various bio-molecular networks, and then discusses the modeling and dynamical analysis of simple genetic circuits, coupled genetic circuits, middle-sized and large-scale biological networks, clarifying the relationships between the structures, dynamics and functions of the networks covered. In the context of large-scale bio-molecular networks, it introduces a number of statistical methods for exploring important bioinformatics applications, including the identification of significant bio-molecules for network medicine and genetic engineering. Lastly, the book describes various state-of-art statistical methods for analysing omics data generated by high-throughput sequencing.

This book is a valuable resource for readers interested in applying systems biology, dynamical systems or complex networks to explore the truth of nature.


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