Erscheint vsl. August 2020 Abbildung von Kleinerman / Gorlick | Current Advances in the Science of Osteosarcoma | 2. Auflage | 2020 | 1258 |

Kleinerman / Gorlick

Current Advances in the Science of Osteosarcoma

Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models

lieferbar ca. 10 Tage als Sonderdruck ohne Rückgaberecht

auch verfügbar als eBook (PDF) für 160.49 €

Buch. Hardcover

2nd ed. 2020. 2020

xiii, 233 S. 11 s/w-Abbildungen, 23 Farbabbildungen, 50 Farbtabellen, Bibliographien

In englischer Sprache

Springer. ISBN 978-3-030-43084-9

Format (B x L): 17,8 x 25,4 cm


This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.

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