Erschienen: 23.08.2016 Abbildung von Ishigatsubo | Behçet's Disease | Softcover reprint of the original 1st ed. 2015 | 2016 | From Genetics to Therapies

Ishigatsubo

Behçet's Disease

From Genetics to Therapies

lieferbar ca. 10 Tage als Sonderdruck ohne Rückgaberecht

ca. 128,39 €

inkl. Mwst.

Softcover reprint of the original 1st ed. 2015 2016. Buch. ix, 176 S. 7 s/w-Abbildungen, 31 Farbabbildungen, 6 s/w-Tabelle, Bibliographien. Softcover

Springer. ISBN 9784431561705

Format (B x L): 15,5 x 23,5 cm

Gewicht: 297 g

In englischer Sprache

Produktbeschreibung

This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease.
Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease:  From Genetics to Therapies  provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.

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