Erschienen: 06.12.1993 Abbildung von Bergeron / Brittenham | The Development of Iron Chelators for Clinical Use | 1993

Bergeron / Brittenham

The Development of Iron Chelators for Clinical Use

lieferbar, ca. 4 Wochen

ca. 385,28 €

inkl. Mwst.

1993. Buch. 432 S. 52 s/w-Tabelle. Hardcover

Taylor & Francis. ISBN 978-0-8493-8679-4

Format (B x L): 15,6 x 23,5 cm

Gewicht: 816 g

In englischer Sprache


Representing an integration of basic and clinical sciences, this book focuses on new concepts in the design, synthesis, and testing of iron chelators for clinical application. It provides an overview of the pathophysiology of iron metabolism as it relates to the origins of iron-mediated tissue damage, and it clearly outlines successes and shortcomings of current iron chelation therapy in preventing such damage. The book also describes a number of other exciting potential therapeutic applications of iron chelators, such as in the treatment of malaria. Other topics covered include iron coordination chemistry, recent advances in synthetic methods for accessing iron chelators, siderophore models, subcellular iron storage targets, and the possible application of biotechnology in the production of therapeutically useful iron chelators. The book also describes new animal models for evaluating chelators.


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